Plenhyage

Intelligent Regeneration. Natural Radiance.

Plenhyage XL is a next-generation injectable that transforms skin from within, using highly purified polynucleotides to awaken the body’s own regenerative power.

Skin Science Meets Cellular Revival

Plenhyage XL works at the cellular level to biologically repair and revitalise tired, damaged or ageing skin. This is regeneration, not just rejuvenation.

  • Visibly improves hydration, firmness, and skin density
  • Calms inflammation, repairs oxidative stress
  • Enhances fibroblast activity and collagen synthesis
  • Creates optimal conditions for lasting skin health

Plenhyage XL from Bioformula is a polynucleotide­ based skin injectable that improves skin elasticity and is effective against ageing, photoaging and for treating fibrous tissues. 
It’s hydrating and anti-free radical activity help create the ideal environment for fibroblast growth, thereby restoring tissue elasticity and promoting cell turnover.

Improved Skin Quality:

By stimulating collagen and elastin production, Plenhyage XL enhances skin firmness, elasticity, and overall quality.

Cell Turnover:

Plenhyage XL promotes cell renewal, aiding in skin repair and addressing issues like acne scarring and sun damage.

Hydration:

The product’s viscoelastic properties and ability to attract water molecules help hydrate the skin, improving its plumpness and hydration.

Anti-free Radical Action:

The product’s polynucleotide chains scavenge harmful OH hydroxyl radicals, protecting skin cells from oxidative stress.
Plenhyage Boxes
Plenhyage XL

Revive the skin from within

Biological skin regeneration

using high-purity salmon-derived DNA

Hydration and elasticity boost

deep water-binding

Stimulates collagen and elastin

for firmer, denser skin

Improves signs of photoageing

dullness, acne scars, and inflammation

The First Step to Intelligent Regeneration

Over time, the skin’s ability to repair and renew itself slows leaving visible signs of damage, dryness, and ageing.

Plenhyage XL supports the skin’s natural intelligence by restoring hydration, reactivating fibroblasts, and rebuilding the cellular environment essential for elasticity and radiance.

  • Restores skin quality following fat loss
  • Restores collagen and elastin for firmer, more elastic skin
  • Reactivates cell turnover and renews the skin barrier

Plenhyage XL in your clinic

Join a growing network of practitioners using regenerative science to deliver natural, clinically proven results.

Offer your patients intelligent skin restoration powered by Italian innovation and CE-certified technology.